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Classification and Labelling
Registry of CLH intentions until outcome

1,4-dioxane

CAS	123-91-1
EC	204-661-8

Basic info

Status	Opinion Adopted
Submitter	Netherlands
Regulatory programme	Chemical registered under REACH
CLP Annex VI Index Number	603-024-00-5
ATP number and date	ATP17 - (11/03/2021), 17/12/2022
Link to ATP	Official Journal [eur-lex.europa.eu]
Remarks	Proposal to change the current classification Carc. 2 into Carc. 1B (CLP) based on new carcinogenicity data.

Classification

Harmonised classification at the time of the proposal	Flam. Liq. 2, H225 Eye Irrit. 2, H319 Carc. 2, H351 STOT SE 3, H335
Proposed harmonised classification by the dossier submitter	Flam. Liq. 2, H225 Eye Irrit. 2, H319 Muta. 2, H341 Carc. 1B, H350 STOT SE 3, H335
Hazard classes open for commenting	Germ cell mutagenicity Carcinogenicity

Intention timeline

Date of intention	2014-08-07
Expected date of submission	2016-06-30
Submitted for accordance check	2016-04-14
Final submission date	2018-02-13
Start of consultation	2018-04-09
Deadline for commenting	2018-06-08
Date of opinion	2019-03-15
Legal deadline for opinion adoption	2019-08-15

Documents

CLH report	external link [echa.europa.eu]
Comments received	external link [echa.europa.eu]
Public consultations - received attachments	external link [echa.europa.eu]
RAC opinion	external link [echa.europa.eu]
Background document	external link [echa.europa.eu]

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1,4-dioxane
CAS: 123-91-1, EC: 204-661-8

Harmonised classification and labelling (CLP Annex VI)
Hazard Class and Category Codes: Flam. Liq. 2: Flammable liquid; Carc. 2: Carcinogenicity; Eye Irrit. 2: Serious eye damage/eye irritation; STOT SE 3: Specific target organ toxicity — single exposure
Registry of SVHC intentions until outcome
Scope: Carcinogenic (Article 57a), Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health), Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Candidate List of SVHCs for Authorisation
Scope: Carcinogenic (Article 57a), Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health), Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
Registrants
Tonnage band: ≥ 1000 to < 10000 tonnes
Registered substances
Tonnage band: ≥ 1000 to < 10000 tonnes

The following timeline shows when we detected changes of this regulatory record (the date might slightly differ from the date of the actual change). Additions between versions are hightlighted in green color, red color shows data removed between versions.

This version

Dec. 10, 2021

ATP number and date: ATP17 - (11/03/2021), 17/12/2022
Link to ATP / File Title: Official Journal
Link to ATP / Full Path: https://eur-lex.europa.eu/legal-content/EN/TXT/HTML/?uri=CELEX:32021R0849&from=EN

Previous version

July 26, 2019

Comments received: https://echa.europa.eu/documents/10162/633e7e10-2a81-3b8f-2b17-3a04618bfad4

Previous version #2

July 1, 2019

Comments received: https://echa.europa.eu/documents/10162/633e7e10-2a81-3b8f-2b17-3a04618bfad4

Previous version #3

May 29, 2019

Background document: https://echa.europa.eu/documents/10162/ed1838af-6db3-dc48-fae4-3a04cdda3ea6
Comments received: https://echa.europa.eu/documents/10162/16251c6c-1977-b013-5f9a-1cc94a95fc56 → https://echa.europa.eu/documents/10162/046a66f4-0f76-6e60-dfc6-aa368cd02ea3
RAC opinion: https://echa.europa.eu/documents/10162/024a7c7e-eb2a-827d-0d88-5ef4a48e932e