methyl 3-(4-chlorophenyl)-3-[[](2S)-3-methyl-2-{[[](propan-2-yloxy)carbonyl]amino}butanamido]propanoate

CAS283159-90-0
EC608-192-3

List details

Basic info

Status Opinion Adopted
Submitter Hungary
Submitter email clh.dossier@nnk.gov.hu
Regulatory programme
  • Active substance in Plant Protection Products

Classification

Proposed harmonised classification by the dossier submitter
  • Aquatic Chronic 2, H411
Hazard classes open for commenting Explosive Flammable solid Self-heating substance or mixture Oxidising solid Acute toxicity Skin corrosion/irritation Serious eye damage/eye irritation Skin sensitization Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity — single exposure Specific target organ toxicity — repeated exposure Hazardous to the aquatic environment Hazardous for the ozone layer

Intention timeline

Date of intention 2015-11-20
Expected date of submission 2018-01-10
Submitted for accordance check 2018-01-12
Final submission date 2019-11-14
Start of consultation 2020-02-03
Deadline for commenting 2020-04-03
Date of opinion 2020-12-10
Legal deadline for opinion adoption 2021-05-15

Documents

CLH report
Annexes to the CLH Report
Comments received
Public consultations - received attachments
RAC opinion
Background document

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Record history

The following timeline shows when we detected changes of this regulatory record (the date might slightly differ from the date of the actual change). Additions between versions are hightlighted in green color, red color shows data removed between versions.

This version
Feb. 18, 2021
  • Background document: https://echa.europa.eu/documents/10162/c070a636-b3b3-a413-7cb8-e124ce884e83
  • Comments received: https://echa.europa.eu/documents/10162/3e48a85f-b7c9-b2e3-4c76-6a7f06ced21bhttps://echa.europa.eu/documents/10162/3f31315a-88f8-608a-53ba-8e9a51b9a647
  • RAC opinion: https://echa.europa.eu/documents/10162/3e3e9cb5-0163-d3c8-5a53-6d1c39e3fdc7
Jan. 19, 2021
  • Date of opinion: 2020-12-10
  • Status: Opinion DevelopmentOpinion Adopted
April 20, 2020
  • Comments received: https://echa.europa.eu/documents/10162/3e48a85f-b7c9-b2e3-4c76-6a7f06ced21b
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/0845f9fc-3aca-d6fa-3614-237e0b3b3780
March 16, 2020
  • Hazard classes open for commenting: To be amended at resubmission: • All hazards to human health with the exception of respiratory sensitisation • Explosives • Flammable solids • Self-heating substances • Oxidising solids • Environmental hazards • Hazardous to the ozone layerExplosive Flammable solid Self-heating substance or mixture Oxidising solid Acute toxicity Skin corrosion/irritation Serious eye damage/eye irritation Skin sensitization Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity — single exposure Specific target organ toxicity — repeated exposure Hazardous to the aquatic environment Hazardous for the ozone layer
  • Remarks: Potential endpoint is Aquatic Chronic 2, H411 and no classification for other endpoints (human and physical hazards)
  • Submitter email: clh.dossier@nnk.gov.hu
Feb. 13, 2020
  • Name: Methyl-3-(4-chlorophenyl)-3-((N-(isopropylcarbonyl)-L-valyl)amino)propanoatemethyl 3-(4-chlorophenyl)-3-[[](2S)-3-methyl-2-{[[](propan-2-yloxy)carbonyl]amino}butanamido]propanoate
Feb. 4, 2020
  • Annexes to the CLH Report: https://echa.europa.eu/documents/10162/96f16105-f216-11a6-62dd-8046dbfe499c
  • CLH report: https://echa.europa.eu/documents/10162/e86ec5ae-1506-9960-9974-d396ad5a9fa0
  • Deadline for commenting: 2020-04-03
  • Final submission date: 2019-11-14
  • Hazard classes open for commenting: To be amended at resubmission: • All hazards to human health with the exception of respiratory sensitisation • Explosives • Flammable solids • Self-heating substances • Oxidising solids • Environmental hazards • Hazardous to the ozone layer
  • Legal deadline for opinion adoption: 2021-05-15
  • Status: SubmittedOpinion Development
  • Start of consultation: 2020-02-03
Sept. 24, 2019
  • Name: methyl 3-(4-chlorophenyl)-3-[(2S)-3-methyl-2-{[(propan-2-yloxy)carbonyl]amino}butanamido]propanoateMethyl-3-(4-chlorophenyl)-3-((N-(isopropylcarbonyl)-L-valyl)amino)propanoate
April 4, 2019
  • Regulatory programme: PPPActive substance in Plant Protection Products
Feb. 18, 2019
  • Regulatory programme: Active substance in Plant Protection Products (in the meaning of Directive 91/414/EEC)PPP
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