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metribuzin (ISO); 4-amino-6-tert-butyl-3-methylthio-1,2,4-triazin-5(4H)-one

CAS21087-64-9
EC244-209-7

List details

Basic info

Status Opinion Development
Submitter Estonia
Submitter email kemikaal@terviseamet.ee
Regulatory programme
  • Active substance in Plant Protection Products
CLP Annex VI Index Number
  • 606-034-00-8

Classification

Harmonised classification at the time of the proposal
  • Acute Tox. 4*, H302
  • Aquatic Acute 1, H400
  • Aquatic Acute 1, M-factor=10
  • Aquatic Chronic 1, H410
  • Aquatic Chronic 1, M-factor=10
Proposed harmonised classification by the dossier submitter
  • Acute Tox. 4, H302
  • STOT RE 2, H373
  • Aquatic Acute 1, H400
  • Aquatic Acute 1, M-factor=10
  • Aquatic Chronic 1, H410
  • Aquatic Chronic 1, M-factor=10
Hazard classes open for commenting Carcinogenicity Germ cell mutagenicity Reproductive toxicity Acute Toxicity - inhalation Acute Toxicity - dermal Acute Toxicity - oral Specific target organ toxicity – single exposure Specific target organ toxicity – repeated exposure Skin corrosion/irritation Serious eye damage/eye irritation Respiratory sensitisation Skin Sensitisation Hazardous to the aquatic environment
Proposed specific concentration limits by the dossier submitter ATE 322 mg/kg bw

Intention timeline

Date of intention 2018-11-16
Expected date of submission 2019-12-20
Submitted for accordance check 2019-12-20
Final submission date 2020-07-02
Start of consultation 2020-08-03
Deadline for commenting 2020-10-02
Legal deadline for opinion adoption 2022-01-01

Documents

CLH report

Related substances

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  • metribuzin
    CAS: 21087-64-9, EC: 244-209-7

Related regulatory records

  • Harmonised classification and labelling (CLP Annex VI) under the name 4-amino-6-tert-butyl-3-methylthio-1,2,4-triazin-5(4H)-one (metribuzin (ISO); 4-amino-4,5-dihydro-6-(1,1-dimethylethyl)-3-methylthio-1,2,4-triazin-5-one)
    Hazard Class and Category Codes: Acute Tox. 4 *: Acute toxicity; Aquatic Acute 1: Hazardous to the aquatic environment; Aquatic Chronic 1: Hazardous to the aquatic environment
  • Registry of CLH intentions until outcome
    Deadline for commenting: 2020-10-02

Record history

The following timeline shows when we detected changes of this regulatory record (the date might slightly differ from the date of the actual change). Additions between versions are hightlighted in green color, red color shows data removed between versions.

Oct. 27, 2020
  • Comments received: https://echa.europa.eu/documents/10162/28ba5043-bbdf-3626-5a99-7ccad69979ba
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/3816c24b-3fa8-e454-5aac-ee42013446fc
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/480adf7d-d637-a255-3570-a74fd75d5ba6
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/4f0e2748-83d0-a8fb-7027-ef24796c91fa
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/6f9a0c92-4737-416f-1b0e-883da9514acc
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/979b1e10-5f23-f22d-a497-06119446d074
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/a8cc8d5c-ef37-28b6-8df9-e90f3b2a55d2
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/c10516ac-b043-6e62-1dab-781a3e661671
This version
Oct. 14, 2020
  • Status: ConsultationOpinion Development
Aug. 5, 2020
  • CLH report: https://echa.europa.eu/documents/10162/88d7329b-fb71-04b6-c27e-12be895c0745
  • Deadline for commenting: 2020-10-02
  • Final submission date: 2020-07-02
  • Hazard classes open for commenting: Carcinogenicity Germ cell mutagenicity Reproductive toxicity Acute Toxicity - inhalation Acute Toxicity - dermal Acute Toxicity - oral Specific target organ toxicity – single exposure Specific target organ toxicity – repeated exposure Skin corrosion/irritation Serious eye damage/eye irritation Respiratory sensitisation Skin Sensitisation Hazardous to the aquatic environment
  • Legal deadline for opinion adoption: 2022-01-01
  • Status: SubmittedConsultation
  • Start of consultation: 2020-08-03
  • Submitter email: kookemikaal@terviseamet.eekemikaal@terviseamet.ee
June 15, 2020
  • Proposed specific concentration limits by the dossier submitter: ATE 322 mg/kg bw
March 16, 2020
  • Submitter email: kookemikaal@terviseamet.ee
Feb. 25, 2020
  • Proposed harmonised classification by the dossier submitter: Acute Tox. 4, H302
Feb. 24, 2020
  • Proposed harmonised classification by the dossier submitter: Acute Tox. 4*, H302
Jan. 14, 2020
  • Proposed harmonised classification by the dossier submitter: Specific target organ toxicity - repeated exposureSTOT RE 2, H373
  • Status: IntentionSubmitted
  • Submitted for accordance check: 2019-12-20
June 18, 2019
  • Proposed harmonised classification by the dossier submitter: Specific target organ toxicity – repeated exposureSpecific target organ toxicity - repeated exposure
April 9, 2019
  • Expected date of submission: 2019-03-312019-12-20
April 4, 2019
  • Regulatory programme: PPPActive substance in Plant Protection Products
Feb. 18, 2019
  • Regulatory programme: Active substance in Plant Protection Products under the Annex I Renewal (AIR) process (Regulation (EC) No. 1141/2010 or Regulation (EC) No. 844/2012)PPP
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