difenoconazole (ISO); 1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole; 3-chloro-4-[(2RS,4RS;2RS,4SR)-4-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl]phenyl 4-chlorophenyl ether

CAS119446-68-3
EC601-613-1

List details

Basic info

Status Opinion Development
Submitter Spain
Submitter email sanidadfitos@mscbs.es
Regulatory programme
  • Active substance in Plant Protection Products

Classification

Proposed harmonised classification by the dossier submitter
  • Acute Tox. 4, H302
  • Eye Irrit. 2, H319
  • Aquatic Acute 1, H400
  • Aquatic Acute 1, M-factor=10
  • Aquatic Chronic 1, H410
  • Aquatic Chronic 1, M-factor=10
Hazard classes open for commenting Explosives Flammable solids Self-reactive substances Pyrophoric solids Self-heating solids Substances which in contact with water emit flammable gases Oxidising solids Corrosive to metals Carcinogenicity Germ cell mutagenicity Reproductive toxicity Acute Toxicity - inhalation Acute Toxicity - dermal Acute Toxicity - oral Specific target organ toxicity – single exposure Specific target organ toxicity – repeated exposure Skin corrosion/irritation Serious eye damage/eye irritation Skin Sensitisation Hazardous to the aquatic environment Hazardous to the ozone layer
Proposed specific concentration limits by the dossier submitter Oral: ATE = 1453 mg/kg bw

Intention timeline

Date of intention 2018-08-30
Expected date of submission 2019-12-31
Submitted for accordance check 2019-12-19
Final submission date 2020-03-19
Start of consultation 2020-03-31
Deadline for commenting 2020-06-01
Legal deadline for opinion adoption 2021-09-18

Documents

CLH report
Comments received
Public consultations - received attachments

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Record history

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This version
July 28, 2020
  • CLH report: https://echa.europa.eu/documents/10162/4bf8f69d-cb0d-3ee7-b3a2-cefeccc4c24ehttps://echa.europa.eu/documents/10162/db8e3c74-9c56-9315-e043-1381106a6033
  • Comments received: https://echa.europa.eu/documents/10162/a883fc36-2227-a1c4-650b-1fc467140551https://echa.europa.eu/documents/10162/c2fa8c05-fdd1-c157-74a9-6d7d8960f03a
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/6613a08e-fb51-4a89-db7e-d08c34e5598ehttps://echa.europa.eu/documents/10162/d6a62b8f-21a8-e627-edde-7a17eeabf797
June 10, 2020
  • Comments received: https://echa.europa.eu/documents/10162/a883fc36-2227-a1c4-650b-1fc467140551
  • Public consultations - received attachments: https://echa.europa.eu/documents/10162/6613a08e-fb51-4a89-db7e-d08c34e5598e
April 2, 2020
  • CLH report: https://echa.europa.eu/documents/10162/4bf8f69d-cb0d-3ee7-b3a2-cefeccc4c24e
  • Deadline for commenting: 2020-06-01
  • Final submission date: 2020-03-19
  • Hazard classes open for commenting: Explosives Flammable solids Self-reactive substances Pyrophoric solids Self-heating solids Substances which in contact with water emit flammable gases Oxidising solids Corrosive to metals Carcinogenicity Germ cell mutagenicity Reproductive toxicity Acute Toxicity - inhalation Acute Toxicity - dermal Acute Toxicity - oral Specific target organ toxicity – single exposure Specific target organ toxicity – repeated exposure Skin corrosion/irritation Serious eye damage/eye irritation Skin Sensitisation Hazardous to the aquatic environment Hazardous to the ozone layer
  • Legal deadline for opinion adoption: 2021-09-18
  • Status: SubmittedOpinion Development
  • Start of consultation: 2020-03-31
March 10, 2020
  • Submitter email: sanidadfitos@mscbs.es
Jan. 14, 2020
  • Proposed harmonised classification by the dossier submitter: Aquatic Acute 1, M-factor=10
  • Proposed harmonised classification by the dossier submitter: Aquatic Chronic 1, M-factor=10
  • Proposed specific concentration limits by the dossier submitter: Oral: ATE = 1453 mg/kg bw
  • Status: IntentionSubmitted
  • Submitted for accordance check: 2019-12-19
April 4, 2019
  • Regulatory programme: PPPActive substance in Plant Protection Products
Feb. 18, 2019
  • Regulatory programme: Active substance in Plant Protection Products under the Annex I Renewal (AIR) process (Regulation (EC) No. 1141/2010 or Regulation (EC) No. 844/2012)PPP
Oct. 12, 2018
  • Name: 1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazoledifenoconazole (ISO); 1-({2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole; 3-chloro-4-[(2RS,4RS;2RS,4SR)-4-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-yl]phenyl 4-chlorophenyl ether
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