Changes March 6, 2019

Besides the usual monthly movement on the list of REACH registrants, this month we see an interesting phenomenon where companies shift their registrations from their UK subdivisions into the continental EU in preparation for Brexit.

Registrants

• (+)-L-arginine hydrochloride
• (+)-bornan-2-one
• (+)-tartaric acid
• (-)-tartaric acid
• (10E)-1-oxacycloheptadec-10-en-2-one
• (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid
• (1R,5S)-3-benzyl-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione
• (2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate
• (2-butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone
• (2-methoxyethyl)benzene
• (2-methoxymethylethoxy)propanol
• (2E)-2-(phenylmethylidene)octanal
• (2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol
• (2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol
• (2E)-2-methyl-3-(4-methylphenyl)prop-2-en-1-ol
• (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol; (2R)-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol; (2R)-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol; (2R)-2,8-dimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol
• (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal (3S,4R,5S)-1,3,4,5,6-pentahydroxyhexan-2-one hydrate
• (2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoic acid
• (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate
• (3-chloro-2-hydroxypropyl)trimethylammonium chloride
• (3-fluoro-4'-pentyl[1,1'-biphenyl]-4-yl)-boronic acid
• (3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde
• (3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}-hexahydropyrrolo[1,2-c][1,3]oxazole-1,5-dione
• (3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
• (3aR,6S)-8,8-dimethyl-4,5,6,7-tetrahydro-3a,6-methano-2,1-benzothiazole 2,2-dioxide
• (4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one
• (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline
• (5-ethyl-1,3-dioxan-5-yl)methyl acrylate
• (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate
• (5R)-5-[(1S)-1,2-Dihydroxyethyl]-4-ethoxy-3-hydroxyfuran-2(5H)-one
• (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2,5-dihydrofuran-2-one
• (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
• (6-aminohexyl)carbamic acid
• (6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)
• (E)-1-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2-buten-1-one
• (E)-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-buten-1-one
• (E)-2-methoxy-4-(prop-1-enyl)phenol
• (E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene
• (E)-N-(pentan-2-ylidene)hydroxylamine
• (E)-N-[1-(naphthalen-1-yl)ethylidene]hydroxylamine
• (E)-anethole
• (R)-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide
• (R)-3,7-dimethyl-1,6-octadien-3-ol
• (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
• (R)-p-mentha-1,8-diene
• (S)-4-{[1-(2-Benzyloxycarbonylamino-acetyl)-(S)-2-methyl-pyrrolidine-2-carbonyl]-amino}-5-oxo-hexanoic acid
• (S)-α-hydroxy-3-phenoxy-benzeneacetonitrile
• (Z)-1-{3-hydroxy-4-[(E)-2-(1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]phenyl}-2-{3-hydroxy-4-[(E)-2-[1-hydroxy-3-sulfo-6-(trihydroxy-lambda4-sulfanyl)naphthalen-2-yl]diazen-1-yl]phenyl}diazen-1-ium-1-olate
• (Z)-3-hexenyl salicylate
• (Z)-N-9-octadecenylpropane-1,3-diamine
• (Z)-docos-13-enamide
• (Z)-octadec-9-enylamine, C16-18-(even numbered, saturated and unsaturated)-alkylamines
• (benzoato-O,O')hydroxy(octadecanoato-O,O')aluminium
• (carboxymethyl)dimethyl-3-[(1-oxododecyl)amino]propylammonium hydroxide
• (cyclohex-3-en-1-yl)methyl 2-hydroxypropanoate
• (ethyl-3-oxobutanoato-O'1,O'3)(2-dimethylaminoethanolato)(1-methoxypropan-2-olato)aluminium(III), dimerised
• (p-ammoniophenyl)bis(2-hydroxyethyl)ammonium sulphate
• (xylenes and 4-ethylbenzene)sulfonic acids
• 0228_Aromatic hydrocarbons, naphthalene content > 1%
• 1'-acetonaphthone
• 1,1'-(1,3-phenylene)bis-1H-pyrrole-2,5-dione
• 1,1'-(ethane-1,2-diyl)bis[pentabromobenzene]
• 1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene]
• 1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromopropoxy)benzene]
• 1,1'-(methylenedi-p-phenylene)bismaleimide
• 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol
• 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol
• 1,1'-Methylenebis(4-isocyanatobenzene) and oligomeric reaction products of 1,1'-methylenebis(4-isocyanatobenzene) and oxydipropanol
• 1,1'-[(6-phenyl-1,3,5-triazine-2,4-diyl)diimino]bisanthraquinone
• 1,1'-azobis(1-cyclohexanecarbonitrile)
• 1,1'-iminodipropan-2-ol
• 1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol
• 1,1'-isopropylidenebis[4-(allyloxy)-3,5-dibromobenzene]
• 1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol
• 1,1,1,2,2,3,3-heptafluoro-3-[(trifluorovinyl)oxy]propane
• 1,1,1,3,3,3-hexamethyldisilazane
• 1,1,1,3,3-pentafluoropropane
• 1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane
• 1,1,1,3,5,5,5-heptamethyltrisiloxane
• 1,1,1-trifluoroacetone
• 1,1,1-trifluoroethane
• 1,1,3,3-tetramethyl-1,3-divinyldisiloxane
• 1,1,3,3-tetramethyldisiloxane
• 1,1,3,3-tetramethyldisiloxane
• 1,1,3,3-tetramethylguanidine
• 1,1-difluoroethane
• 1,1’-Methylenebis(4-isocyanatobenzene) and its reaction products with [(methylethylene)bis(oxy)]dipropanol, butane-1,3-diol and propylene glycol
• 1,2,2,6,6-pentamethylpiperidin-4-ol
• 1,2,3,6-tetrahydrophthalic anhydride
• 1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich
• 1,2-Dihydro-2,2,4-trimethylquinoline, oligomers
• 1,2-benzisothiazol-3(2H)-one
• 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt
• 1,2-dibromoethane
• 1,2-dichloroethane
• 1,2-diethoxypropane
• 1,2-difluoro-3-methoxy-6-[4-(trans-4-propylcyclohexyl)-1-cyclohexen-1-yl]-benzene